09 April 2005

Grow your own stem cells?

As a child I was an avid fan of the Spider Man comic strips. One of Spidey's foes was a scientist who had lost an arm in an accident and was experimenting using lizards to see if he could regenerate his arm. He succeeds but the cost is that he becomes the Lizard Man and not a nice person to know any longer. Using a protein from newts, some scientists found that they could convert muscle cesll of mice into stem cells. If only the Lizard Man had used mice first!

Anyway, it could point the way to a win-win solution on the stem cells question.
"I believe that dedifferentiation -- the direct conversion of a somatic cell into an embryonic stem cell -- is the holy grail for those seeking morally acceptable alternatives to the destructive embryo research now required to obtain (embryonic stem) cells,' said Father Nicanor Austriaco, a molecular biologist and Catholic priest in Washington, D.C. 'You would also be able to get immunocompatible (embryonic stem) cells from every patient by simply dedifferentiating his or her cells. This would be an amazing discovery."
However, we should recall that research is at a very early stage yet. But -if I'm not mistaken- it also could be significant for those with nerve damage such as paraplegics. I suspect that regrwoing limbs is quite a way off as that would also involve learning how to grow the stem cells in sequences probably with quite a sophisticated cocktail of hormones and timings.
Wired News: Cells That Go Back in Time:

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